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Level 13

Glycolysis


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Another name for catabolism is...
cellular respiration
Another name for anabolism is ...
cellular biosynthesis
Catabolic reactions transfer energy from complex molecules to...
ATP
Anabolic reactions transfer energy from ATP to...
complex molecules
What happens during the energy investment phase of glycolysis?
Glucose is broken down to G3P while consuming 2 ATP
What happens during the energy payoff phase of glycolysis?
2G3P is converted to pyruvate while energy is harvested as 4 ATP and 2 NADH
Glycolysis happens in which cell compartment?
In the cytosol
The hexokinase catalyzes the first step of glycolysis which...
phosphorylates glucose at the 6 C-atom, while consuming ATP
The phosphogluco-isomerase converts glucose-6-phosphate to an isomer called...
fructose-6-phosphate
Glucose and fructose have the same molecular formula C6H12O6 but the nature of their functional group differs ...
one is a ketol (Fru) and the other an aldehyde (Glu)
Fructose-6-phosphate is phosphorylates by phospho-fructokinase to form...
fructose-1,6-bisphosphate
Why do we need biphosphorylated fructose?
because it can be symetrically broken down to 3C-atom molecules like G3P and DHAP
How many 3C atom molecules are produced from 1 molecule of glucose?
Two 3C-atom molecules a G3P (glyceraldehyde-3-phosphate) and DHAP(dihydroxyacetone phosphate)
What happens to DHAP when G3P is consumed by a triose phosphate dehydrogenase?
DHAP is converted by an isomerase to G3P which will continue to fuel the dehydrogenase
The triose-phosphate-dehydrogenase catalyzes the only...
redox reaction of glycolysis producing 2 NADPH, and a 1,3 biphosphoglycerate
The triose-phosphate-dehydrogenase adds a second phosphate group on 1,3 biphosphoglycerate by using...
one phosphate group from pyrophosphate (Pi)
What happens when a 1,3 biphosphoglycerate is converted to 3-phosphoglycerate by a phosphoglycerokinase?
an ATP is produced
The phosphoglyceromutase converts 3-phosphoglycerate to ...
2-phosphoglycerate
Why does the phosphoglyceromutase converts 3-phosphoglycerate to 2-phosphoglycerate?
Because the second C-atom is where a new carbonyl-group should from in order to make pyruvate
The enolase two 2-phosphoglycerates to two phosphoenolpyruvate by removing ...
two water molecules
Pyruvate kinase converts phosphoenol-pyruvate to ...
pyruvate while producing ATP
How many pyruvates are made per molecule of glucose?
two pyruvates.