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Level 21

Musculoskeletal (drug side effects)


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nausea, diarrhoea, GI bleed, GI ulcer
NSAIDs
hypersensitivity reactions (e.g. rash, angioedema), bronchospasm, headache, dizziness
NSAIDs
fluid retention, renal failure
NSAIDs
small increased risk of thrombotic events
NSAIDs
potentiate warfarin
NSAIDs
lowest risk of GI effects
Ibuprofen
bleeding risk
Aspirin
nausea, vomiting, diarrhoea, abdo pain
Colchicine
peripheral neuropathy, myositis
Colchicine (rare)
rash, may progress to more serious skin reaction
Allopurinol
hypersensitivity reactions including exfoliation, fever, lymphadenopathy, arthralgia, eosinophilia
Allopurinol (rare)
GI disorders, malaise, headache, dizziness
Allopurinol (rare)
anorexia, nausea, low wbc, hepatitis
Methotrexate
teratogenic
Methotrexate
myelosuppression, hepatic fibrosis, pneumonitis
Methotrexate
fever, bruising, neutropaenia, myelosuppression
Sulfasalazine
macular changes
Hydroxychloroquine
fever, bruising, myelosuppression
Azathioprine
increased risk of infections, especially TB
Anti TNF-α drugs
rash, allergic reaction, increased risk of infections
Anti B cell drugs