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Level 3

Cardiovascular (drug side effects)


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dry cough, hyperkalaemia, angioedema, first dose hypotension
ACE inhibitors
renal impairment if reduced afferent arteriole flow (e.g. NSAIDs, renal artery stenosis)
ACE inhibitors
similar to ACE inhibitors, but lower incidence of cough and hyperkalaemia
AR blockers
increased sympathetic activity, negative inotropic effects
Non-dihydropyridine calcium channel blockers
headache, constipation, oedema
Calcium channel blockers
sleep disturbance
Lipid-soluble beta blockers e.g. propranolol
reduce dose in renal failure
Water-soluble beta blockers e.g. bisoprolol
bronchospasm, fatigue, sexual dysfunction
Beta blockers
increased risk of glucose intolerance in diabetes
Beta blockers
nausea, vomiting, diarrhoea
Digoxin
arrhythmias, conduction disturbances
Digoxin
dizziness, blurred vision, yellow vision
Digoxin
hypokalaemia, hyponatraemia, hyperuricaemia, raised creatinine
Loop diuretics
fatigue, hypotension
Loop diuretics
exacerbation of diabetes and gout
Loop diuretics
hyperkalaemia
Aldosterone antagonists
gynaecomastia
Aldosterone antagonists
hypokalaemia, hyponatraemia, hyperglycaemia
Thiazide and related diuretics
postural hypotension
Thiazide and related diuretics
gout
Thiazide and related diuretics
chest pain, bronchospasm, flushing
Adenosine
small chance of inducing AF
Adenosine
thyroid and liver dysfunction
Amiodarone
pneumonitis (CXR prior to treatment)
Amiodarone
reversible corneal deposits and skin pigmentation
Amiodarone
drug interactions, especially warfarin and digoxin
Amiodarone
oedema, dyspnoea
Flecainide
dizziness, fatigue, fever
Flecainide
visual disturbances
Flecainide