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Diabetes & Endocrinology (drug use)


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Metformin
type 2 diabetes (first line)
Sulphonylureas
type 2 diabetes (second line)
Insulin
type 2 diabetes (third line), type 1 diabetes (first line)
Gliptins
type 2 diabetes (used with insulin)
Pioglitazone
type 2 diabetes (used with insulin)
10-20 g glucose
hypoglycaemia (pt conscious)
50 ml IV glucose
hypoglycaemia (pt unconscious)
SC or IM glucagon
hypoglycaemia (pt unconscious)
Long term anti-thyroid drug treatment
Grave's disease (first line)
Radioactive iodine
Grave's disease (second line)
Radioactive iodine
multinodular goitre
Beta blockers
hyperthyroidism (symptom control)
IV fluids + beta blockers + corticosteroids + iodine + anti-thyroid drugs
thyrotoxic crisis ('thyroid storm')
Hormone replacement
hypothyroidism
Oral cortisol + mineralocorticoid
Addison's disease
IV cortisol
acute adrenocortical insufficiency
Cortisol
hypopituitarism
Bisphosphonates
osteoporosis (first line)
Calcitonin
osteoporosis (second line)
Raloxifen
osteoporosis (third line)
IV saline 4-6L in 24hrs
acute hypercalcaemia
Bisphosphonates
acute hypercalcaemia
Glucocorticoids
acute hypercalcaemia in lymphoma
Prednisolone
hypercalcaemia (effective in 2-4 days)
Calcitonin
acute hypercalcaemia (second line)