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Level 35

CVRR 09 (I)


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Thrombus
A term used to describe a blood clot
Prostacyclin, NO
Intact endothelium produces [_______] and [__], which prevents platelets from adhering
Plug formation
Damaged endothelium leads to [_______]
Haemostasis
A term used to describe an interruption of blood flow
Plasmin protein
Platelet plugs (clots) are dissolved naturally by [_______]
Embolus
A term used to describe a clot which has detached from its vessel wall and moved elsewhere in the body
Platelet factors, attracts more platelets
After platelets adhere together, they release [_______], which [_______]
Metabolic hyperaemia
A term used to describe an increase in blood flow caused due to by-products of cellular respiration
O2 carrying capacity of the blood and coronary blood flow
The factors influencing myocardial oxygen supply
Wall stress/tension, heart rate and contractility
The factors influencing myocardial oxygen demand
Perfusion pressure and vascular resistance
The factors influencing coronary blood flow
Adenosine
A potent vasodilator capable of over-ruling the effects of α-1 stimulation
LDL, oxidised, monocytes, macrophages
The key stages of the evolution of atheromatous plaque. [_______], [_______], [_______], [_______], foam cells, smooth muscle cells and fibrous plaque
Foam cells, smooth muscle cells and fibrous plaque
The key stages of the evolution of atheromatous plaque. LDL, oxidised, monocytes, macrophages, [_______], [_______] and [_______]
Dilate, preload, myocardial demand
GTN's main benefit is to [______] veins. This reduces venous return, which reduces [_______]. By taking this stress off the heart, [_______] decreases