Level 53 Level 55
Level 54

CVRR 45 Oxygen Transport and Hypoxia


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0.27 kPa
The critical mitochondrial PO2 in kPa - i.e. the lowest possible partial pressure of oxygen before mitochondria stop working
SaO2
The percentage saturation of arterial blood with oxygen
SvO2
The percentage saturation of venous blood with oxygen
HbO2 = SaO2 x Hb x 1.34
The equation for calculating the HbO2 of arterial blood - the amount of oxygen carried on the haemoglobin of arterial blood
Dissolved O2 = PaO2 from curve x 0.003
The equation for calculating the amount of dissolved O2 in arterial blood
CaO2 = HbO2 + Dissolved O2
The equation for calculating CaO2 = the total amount of oxygen carried in arterial blood
DO2 = CaO2 x CO x 10
The equation for calculating DO2 - oxygen delivery to the body
HbO2 = SvO2 x Hb x 1.34
The equation for calculating the HbO2 of venous blood - the amount of oxygen carried on the haemoglobin of venous blood
Dissolved O2 = PvO2 from curve x 0.003
The equation for calculating the amount of dissolved O2 in venous blood
CvO2 = HbO2 + Dissolved O2
The equation for calculating CvO2 = the total amount of oxygen carried in venous blood
OER = (CaO2 - CvO2) / CaO2
The equation for calculating the oxygen extraction ratio
Hypoxic hypoxia
A type of hypoxia where the PO2 of arterial blood is reduced
Anaemic hypoxia
A type of hypoxia where the PaO2 is normal but [Hb] is reduced
Stagnant or ischaemic hypoxia
A type of hypoxia where the PaO2 and [Hb] are normal but blood flow is low
Histotoxic or cellular hypoxia
A type of hypoxia where tissue DO2 (oxygen delivery) is normal but cells cannot use O2 due to a toxic factor