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CVRR 67 Loop of Henle


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Loop of Henle
Nephron: LoH
Descending thin limb, ascending thin limb and thick ascending limb
The three segments of the Loop of Henle, in order of occurrence
Descending thin limb, ascending thin limb and thick ascending limb
Nephron: DTL, ATL and TAL
Thick ascending limb
Part of the renal tubule that Is impermeable to water and contains many mitochondria for the active reabsorption of ions.
Na+ K+ ATPase Pump
Ion pump responsible for reabsorption of solute in TAL of LoH
Descending limb
A whole limb of the Loop of Henle that has a high permeability to water and low permeability to solute
Ascending limb
A whole limb of the Loop of Henle that is impermeable to water and is very active in reabsorbing solute
15%
Juxtamedullary nephrons account for this percentage of all nephrons in our kidneys
Counter-Current Multiplication
A process carried out by the Loop of Henle which leaves tubular fluid hypo-osmotic with respect to plasma.
NaCl
Accumulates in the interstitium after reabsorption, a process critical later for the production of hyper-osmotic urine (if necessary)
Vasa recta
Peritubular capillaries which wrap around juxtamedullary LoHs preserving the concentration gradient
12% NaCl
The Distal tubule and Collecting duct reabsorbs [__]% of filtered [___]
Diluted
If water intake is in excess of needs, urine must be [diluted/concentrated]
Concentrated
If water intake is short of needs, urine must be [diluted/concentrated]
Antidiuretic hormone
A hormone which regulates the body's retention of water by acting to increase water absorption in the collecting ducts of the nephron
ADH
When the body needs to retain water, this hormone is released
Four
The maximum concentration of urine that the human kidney can acheive is [___] times that of plasma
Na, Cl and H2O
The Loop of Henle reabsorbs 20% of [__], [__] and [__]
Hypo-osmotic 150
Tubular fluid leaving the Loop of Henle is [_______] compared to the plasma, at ~[__] mOsm/L
Vasopressin
ADH is sometimes referred to as this
Permeable
Regarding the Loop of Henle, thin descending limb is [permeable/impermeable] to water
Impermeable
Regarding the Loop of Henle, thick limb is [permeable/impermeable] to water
Thick ascending limb
Reabsorption of ions occurs exclusively in the [_______] of the Loop of Henle
Descending thin limb
Reabsorption of almost 20% of filtered water occurs in the [_______] of the Loop of Henle
50 50
In the thick ascending limb of the loop of Henle [__]% of cations are reabsorbed by paracellular movement, and [__]% by transcellular movement
Slow countercurrent exchange
In the nephron, vasa recta have a [____] flow rate (allows equilibration of osmolarity) and form hairpin loop that creates a [____________] system
Distal tubule
Nephron: DT
Collecting duct
Nephron: CD
Dilute 50
Tubular fluid in the DT and CD is very [dilute/concentrated], at ~[__] mOsm/L
NaCl and thick ascending limb
ADH increases active reabsorption of [____] in the [______] of the Loop of Henle to aid the cortico-medullary osmotic gradient
Cuboidal
The TAL is made up of [_______] epithelia
Simple squamous
The thin limbs of the Loop of Henle are made up of [________] epithelia
Many
The TAL has [many/no] mitochondria
No
The thin limbs of the Loop of Henle have [many/no] mitochondria
Impermeable
Regarding the Loop of Henle, thin ascending limb is [permeable/impermeable] to water