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Petrarch begins teaching in Florence
Donatello produces the bronze free-standing statue of David
Johan Gutenberg invents the printing press
Marsilio Ficino establishes Platonic Academy in Florence
Leonardo paints the Mona Lisa
Michelangelo paints frescoes in the Sistine Chapel
Scholars working in Spain produce the Complutensian Polyglot
Niccoló Machiavelli writes 'The Prince'
Thomas More writes 'Utopia'
François Rabelais publishes the first part of 'Gargantua and Pantagruel'
Giorgio Vasari publishes 'Lives of the Most Eminent Painters, Sculptors, and Architects'
Jean Bodin publishes 'The Six Books of the Republic'
Shakespeare's 'Romeo and Juliet' probably first performed
Miguel de Cervantes publishes the first part of 'Don Quixote'